Urine creatinine: This test measures the amount of creatinine in urine. If the GFR is high then it may indicate chances of kidney failure. The normal value in males is 97 to 137 mL/min and females is 88 to 128mL/min. It is also done to estimate the glomerular filtration rate (GFR). Creatinine is the waste product released when the muscle is put to work. Creatinine levels may be decreased slightly in pregnancy.Ĭreatinine clearance: This test determines the kidney functioning and suggests kidney dysfunction or decreased blood flow to kidneys as in congestive heart failure. If the level of creatinine is more than the normal value it indicates kidney conditions such as glomerulonephritis, pyelonephritis, acute tubular necrosis, kidney stones, prostate disease, and complications of diabetes. Normal value of creatinine is 0.8 – 1.4mg/dL Females have low creatinine than males because of the muscle mass. Creatinine is filtered from blood and excreted in urine by the kidneys. Creatinine is a byproduct of creatine produced when muscles are put to use. Decreased concentration of BUN is not common and may occur in cases of malnutrition and severe kidney disease.īlood Creatinine: This test measures the amount of creatinine in blood which signifies the filtering capability of kidneys. Elevated levels suggest impaired kidney function such as acute or chronic kidney disease, decreased blood flow to kidneys as in congestive heart failure and shock. The normal values of nitrogen in blood urea ranges from 7 to 20mg/dL. Urea is a waste product released from degradation of protein, which is filtered in the blood and excreted in urine by kidneys. ![]() Some of the commonly conducted laboratory tests areīlood urea nitrogen (BUN): The BUN test measures the nitrogen content in blood urea. These tests reveal the functioning and abnormalities, if any. Kidney function tests are the tests performed to evaluate kidney functioning. Kidney :: Prostate :: Urinary Bladder :: Testes Where 60 represents MW of urea and 14*2 MW of urea nitrogen.Home » Patient Info » Genito Urinary System » Kidney » Kidney Function tests Elsewhere, the concentration of urea is reported in SI units as mmol/L.ī U N m g / d L United States, Mexico, Italy, Austria, and Germany). OTC deficiency is also accompanied by hyperammonemia and high orotic acid levels.īUN is usually reported in mg/dL in some countries (e.g. Reference ranges for blood tests, comparing urea (yellow at right) to other blood constituentsĪnother rare cause of a decreased BUN is ornithine transcarbamylase deficiency, which is a genetic disorder inherited in an X-linked recessive pattern. The main causes of a decrease in BUN are malnutrition (low-protein diet), severe liver disease, anabolic state, and syndrome of inappropriate antidiuretic hormone. Hypothyroidism can cause both decreased GFR and hypovolemia, but BUN-to-creatinine ratio has been found to be lowered in hypothyroidism and raised in hyperthyroidism. The main causes of an increase in BUN are: high-protein diet, decrease in glomerular filtration rate (GFR) (suggestive of kidney failure), decrease in blood volume ( hypovolemia), congestive heart failure, gastrointestinal hemorrhage, fever, rapid cell destruction from infections, athletic activity, excessive muscle breakdown, and increased catabolism. The normal range is 2.1–7.1 mmol/ L or 6–20 mg/ dL. ![]() Interpretation īUN is an indication of renal (kidney) health. It is not considered as reliable as creatinine or BUN/creatinine ratio blood studies. The test is used to detect renal problems. Individual laboratories will have different reference ranges, as the assay used can vary between laboratories. Normal human adult blood should contain 6 to 20 mg/dL (2.1 to 7.1 mmol/L) of urea nitrogen. The liver produces urea in the urea cycle as a waste product of the digestion of protein. ![]() 6299-2, 59570-2, 12961-9, 12963-5, 12962-7īlood urea nitrogen ( BUN) is a medical test that measures the amount of urea nitrogen found in blood.
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